Sepsis, the body’s overactive response to infection, is a common cause of foal illness and death. Septic foals show signs of body system collapse, leading to severe pain, prolonged treatment and in some cases euthanasia. A major consequence of sepsis is the loss of the proper hormonal production necessary for normal body function. One of the most important hormones involved in fighting sepsis is cortisol – essential for controlling inflammation and regulating blood sugar and blood pressure in sick patients. Sick foals often have low blood levels of cortisol that can lead to worsening symptoms and death. In this study, researchers will work toward creating a new diagnostic test for hormonal diseases in septic foals. Findings will provide a better understanding of foal sepsis and inform possible new treatment options, improving the survival rate and well-being of foals affected by this devastating and challenging health condition.
Grant amount awarded
North Carolina State University
Katarzyna Dembek, DVM, PhD, DACVIM-LA