Researchers will develop statistical breeding models to help reduce hemangiosarcoma incidence in dog breeds.

Researchers will investigate the prevalence and geographical distribution of koala retrovirus and chlamydia infections in koalas to identify populations with disease-free animals to assist conservation efforts.

Researchers will use state-of-the-art gene editing techniques to identify genes that influence growth and progression of oral squamous cell carcinoma tumors in cats.

SUMMARY: Researchers will evaluate an innovative approach using engineered intracellular bacteria called quasiorganelles as a platform for the intracellular delivery of proteins to histiocytic sarcoma cells and surrounding immune cells in the local tumor environment. This proteins have been selected to suppress cancer growth and stimulate the immune system for the purpose of eliminating cancer cells.

Researchers will evaluate the safety and efficacy of a novel combination of checkpoint inhibitor and adoptive T-cell therapy in giant-breed dogs diagnosed with appendicular osteosarcoma, a type of primary bone cancer of the limbs.

Researchers will standardize and improve organization of data collected from 3,000+ dogs enrolled in Morris Animal Foundation’s Golden Retriever Lifetime Study to expand access and research opportunities.