Developing a New Treatment Strategy for Osteoarthritis
Researchers will explore the potential of gene therapy (reprogramming of cells already present in the body through the transfer of genes) as a new strategy to treat osteoarthritis in dogs.
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Evaluating 3-Day Antibiotic Treatment for Urinary Tract Infections
Researchers will conduct a clinical trial to see if three days of the antibiotic amoxicillin is as effective as seven days for the treatment of urinary tract infections in dogs.
Developing a Broader Leptospirosis Vaccine
Researchers will screen genomes of several strains of bacteria causing leptospirosis, a potentially fatal disease in dogs, to help identify vaccine candidates and improve protection against infections.
Developing Gene-Editing Tools for Heart Disease
Researchers will use novel gene-editing tools to correct damaging mutations in heart cells to help advance gene therapies for dilated cardiomyopathy, a common canine heart disease.
Studying a Genetic Mutation in Osteosarcoma
Researchers will investigate how a genetic mutation affects treatment success for aggressive osteosarcoma.
Investigating Novel Device to Reduce Epileptic Seizures
By examining its effects on a dog’s heart and brain, researchers will investigate a wearable, wireless collar device designed to reduce seizures in canine epilepsy patients.
Designing a Novel Heartworm Vaccine
Researchers will identify antigens (substances that help trigger antibody defenses against disease) as a critical step toward developing a novel vaccine for heartworm in dogs.