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Leptospirosis is a widespread zoonotic bacterial disease that affects numerous animal species. This re-emerging disease increasingly is recognized as a cause of illness and death in dogs. Currently available vaccines only provide protection against a few strains and their protection is short-lived, requiring more frequent vaccination. To improve vaccine duration, and confer protection against a larger number of Leptospira strains, researchers will use a novel strategy to screen genomes of several  known strains of canine leptospirosis. The hope is to identify components (peptides) common to multiple strains that can trigger a protective immune response against multiple strains. Researchers will use this new information to develop an improved vaccine with broader protection and a longer-lasting immune response. 

Study ID
Study Status
Start Date
Grant amount awarded
Grant recipient
The University of Tennessee
Study country
United States
Sreekumari Rajeev, PhD, DACVM, DACVP
Study category
Infectious Disease