Researchers will study the genetic basis of subvalvular aortic stenosis in Newfoundland dogs, a high-risk breed for developing this devastating heart condition.
Researchers will evaluate if the drug rapamycin can reverse the negative heart changes associated with subvalvular aortic stenosis, the most common congenital heart defect in dogs.
Researchers will look for a shared genetic origin of hypertrophic cardiomyopathy, the most diagnosed feline heart disease, across breeds and mixed breeds.
Researchers will look for a shared genetic origin of hypertrophic cardiomyopathy, the most diagnosed feline heart disease, in the general cat population.
Researchers will use novel gene-editing tools to correct damaging mutations in heart cells to help advance gene therapies for dilated cardiomyopathy, a common canine heart disease.