Researchers are exploring if a protein found in some human cancers is also present in hemangiosarcoma tumors, and is a feasible therapy target.

Researchers will investigate how hemangiosarcoma cells use cholesterol and lipids to promote tumor growth and look at ways to block tumor cells from using these metabolic fuels.

Researchers will use a novel approach to differentiate between cancerous and normal cells surrounding splenic hemangiosarcoma tumors to improve successful tumor removal and drug delivery.    

Researchers will study the feasibility of using molecules called microRNAs as an early detection tool for hemangiosarcoma, an often-fatal cancer in dogs.

Researchers will investigate how metabolic processes affect tumor growth andchemotherapy resistance in dogs with hemangiosarcoma and ways to block or disrupt these processes.

SUMMARY: Researchers will identify the volatile organic compound (VOC) profile of hemangiosarcoma using bio-detection dogs as a step toward a diagnostic test for the disease.

Using genotyping data from the Golden Retriever Lifetime Study, researchers will conduct a study to help identify genomic regions involved with increased susceptibility for hemangiosarcoma in American golden retrievers.

Researchers will search for new therapy targets for hemangiosarcoma in dogs to inform the development of much-needed therapies and preventives for this deadly cancer.

SUMMARY: Researchers will investigate whether their newly developed urine testing method, Raman molecular urinalysis (RMU), can detect signs of hemangiosarcoma (HSA).

SUMMARY: Researchers will build on earlier research to assess whether the cell surface marker integrin α6β4 can be used as a treatment target.