Researchers will study the genetic basis of subvalvular aortic stenosis in Newfoundland dogs, a high-risk breed for developing this devastating heart condition.

Researchers will study if toxic heavy metals are associated with increased risk of health challenges in aging dogs, including cognitive decline, hearing loss and visual decline.

Researchers will study age-associated inflammation associated with diseases in aging dogs.

Researchers will study the aging process, including genetically programmed aging “clocks” and anti-aging strategies, in a well-studied population of retired sled dogs.

Researchers will conduct a clinical trial to assess if exercise can reduce frailty and improve health span of frail, elderly dogs.