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Insulin dysregulation is characterized by tissue insulin resistance (inadequate response to insulin) and/or abnormally high insulin response to oral glucose. Insulin dysregulation is a major health concern in horses linked to the development of laminitis, a disease that causes tissue damage within the hoof and severe lameness. The current recommendations for feeding horses with insulin dysregulation is to avoid high starch diets to minimize the insulin response. However, little data exists to support this practice. Researchers will look at the consequences of different dietary carbohydrates on insulin dysregulation. Identifying factors that contribute to the development of this condition is key to developing appropriate dietary recommendations for horses at risk of laminitis.

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Study Status
Start Date
Grant amount awarded
Grant recipient
University of Melbourne
Study country
Nicholas Bamford, PhD
Study category
Endocrine/Metabolic (Diabetes, Thyroid)