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SCIENTIFIC TITLE: Genomic characterization of Herpesviruses and their pathogenic variants in trafficked Neotropical primates

START DATE: Spring 2025

PROJECTED DURATION: 2 years

SUMMARY: Researchers will study genetic information on the herpesviruses infecting trafficked monkeys.

THE PROBLEM: The illegal trade of monkeys is a global problem. It brings humans, monkeys, and other animals into close contact, raising the risk of disease transmission. In Peru, the team found over 20 different herpesviruses in trafficked monkeys. Some monkeys infected with the human herpesvirus HSV-1 die, while others remain healthy. The team found a clue suggesting there might be a genetic difference between the types of HSV-1 that cause severe illness and those that do not. However, researchers don’t fully understand what causes these differences. This lack of understanding is due to insufficient research on the genetic makeup of these viruses. Learning more could help not only infected monkeys but help keep researchers, wildlife managers recovering the monkeys and other animals safe.

THE PROJECT: The goal of the project is to gather detailed genetic information on the herpesviruses infecting trafficked monkeys. The team will analyze the genetic differences between viruses that cause disease and those that do not. Additionally, the team will investigate whether the virus can hide in the brains of monkeys, as it does in humans. 

POTENTIAL IMPACT: The team’s goal is to produce valuable data to improve monkey health and conservation efforts.
 

Study ID
D25ZO-424
Study Status
Active
Grant amount awarded
$144,396
Grant recipient
Tufts University
Study country
Peru
Investigator
Fernando J Vilchez-Delgado, DVM