Understanding How Bacteria Communicate and Promote Infections

Staphylococcus pseudintermedius is the most common opportunistic bacteria on the dog's skin and it is a frequent cause of postoperative infections, especially those associated with medical devices such as orthopedic implants and catheters. Bacteria associated with these infections form biofilms, which are groups of bacteria that stick to each other and adhere to implanted medical devices and other surfaces. Biofilms protect the bacteria from antimicrobial drugs, making infections difficult to treat. Understanding how the signaling system of S. pseudintermedius works and prompts biofilm formation will help researchers develop novel antimicrobial therapies and/or preventive measures to reduce postoperative infections in dogs.