Equine herpesvirus 1 (EHV-1) infection causes respiratory distress, abortion and neurological disease. Despite efforts and vaccination programs to control EHV-1, outbreaks continue to be a major problem threatening horses and related species worldwide, including zebras and rhinoceroses. Researchers will study the first stages of EHV-1 infections to better understand how the virus induces disease using CRISPR technology, a cutting-edge gene editing tool, to verify their findings. New information from this study will help inform the development of better diagnostics and treatments as well as improve EHV-1 control measures.
Grant amount awarded
Freie Universität Berlin
"Differentially-Charged Liposomes Interact with Alphaherpesviruses and Interfere with Virus Entry," Pathogens, May 2020
"Equine Alphaherpesviruses Require Activation of the Small GTPases Rac1 and Cdc42 for Intracellular Transport," Microorganisms, July 2020