Studying the Genetics of Feline Tooth Resorption

Feline tooth resorption is a common and incurable condition in cats that can cause recurrent episodes of oral pain. Despite decades of study into environmental influences for the condition, little is known about the cause of tooth resorption. In human studies, tooth resorption runs in families, suggesting an underlying genetic influence. To find out if this also holds true for cats, researchers will analyze and compare DNA samples from cats affected with tooth resorption to cats that do not have evidence of current or past tooth resorptions. Findings will help paint a genetic picture of tooth resorption – for example if there are a few genes responsible or if many genetic variants influence the condition. This new knowledge will help inform new avenues of research to improve treatment and management of this painful dental condition in cats.