Meningoencephalitis of unknown origin (MUO) is a common autoimmune disorder affecting the nervous system of dogs. Treatments are only partially successful with many dogs suffering long-term illness and even death. Identifying changes in the immune system associated with the disease could point the way toward development of improved treatment strategies. Researchers will use state-of-the-art sequencing of blood cells reflecting different states of the disease, including dogs in remission, to help identify immune system genes that contribute to disease. The team hopes their findings will inform future studies to identify new therapy targets – ultimately broadening treatment options for MUO and extending lifespan and quality of life for affected dogs.
Grant amount awarded
University of Georgia
Renee Barber, DVM
Neurology (Brain and Spinal Cord)