Recent technological breakthroughs have facilitated the discovery of new drugs to fight deadly human viruses, such as Ebola. These drugs are derived from the blood of previous survivors of the disease. However, no similar process exists for the discovery of drugs to treat highly lethal viruses of equids, such as African horse sickness – a viral disease with mortality rates as high as 90% in affected horses. Researchers will establish the technologies needed using the blood of immunized horses to discover similar immunotherapeutic drugs to fight deadly equine viruses. This pilot study will establish a template technology protocol to help facilitate discovery of novel immunotherapeutics against all equine infections as well as inform future vaccine designs.
Grant amount awarded
National Institute for Communicable Diseases
Constantinos Kurt Wibmur, PhD