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Mast cells play a part in acute and chronic asthma in horses, but their precise role has not been clearly defined. In humans, healthy and asthmatic patients have different airway mast cell subtypes and this finding has led to better diagnostics and targeted therapies. In this study, researchers will characterize and compare mast cell subtypes found in the airways of healthy horses and horses with either recurrent airway obstruction or inflammatory airway disease, two common types of equine asthma. This new information will provide a platform for further investigations to improve diagnostics and help identify new therapeutic targets for horses with asthma.

Study ID
D18EQ-830
Study Status
Active
Start Date
02/01/2018
Grant amount awarded
$10,800
Grant recipient
The University of Tennessee
Study country
United States
Investigator
Jane S. Woodrow,, MSc, DVM
Study category
Respiratory