Researchers will study how changes in the gut’s microbial composition may contribute to chronic intestinal disorders and associated inflammation in dogs and if dietary supplements can help alleviate clinical signs for these patients.
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Researchers are studying if hemangiosarcoma subtypes influence how affected dogs respond to treatment – a step toward precision medicine for these patients.
Researchers will develop statistical breeding models to help reduce hemangiosarcoma incidence in dog breeds.
Researchers will investigate the role of a genetic mutation found in about one third of dogs diagnosed with hemangiosarcoma, in an effort to find new therapies for dogs affected by this aggressive and highly metastatic cancer.
Researchers will study the feasibility of using molecules called microRNAs as an early detection tool for hemangiosarcoma, an often-fatal cancer in dogs.
Researchers are exploring if a protein found in some human cancers is also present in hemangiosarcoma tumors, and is a feasible therapy target.
Researchers will use a technique called single-cell RNA sequencing to identify surface markers specific to canine hemangiosarcoma cells as a first step toward the development of a more effective and precise therapy.