Researchers are investigating the effectiveness of a novel immunotherapy to help reduce metastatic disease (cancer spread) and prolong quality of life in dogs with osteosarcoma.
Researchers will investigate the role of a signaling pathway in the progression of bone cancer in dogs and evaluate its potential as a new therapeutic target to help treat this disease.
Researchers will explore metabolic drivers of cancer growth and look for new therapy targets for osteosarcoma, the most common type of bone cancer in dogs.
This study will characterize the expression of toll-like receptors, which activate the immune system, in canine osteosarcoma cells to better determine the biological consequences associated with activating these receptors.
Researchers are studying a group of 80 dogs with osteosarcoma to generate comparison data for ongoing and future studies of new chemotherapeutic agents.