Researchers will determine if common heart medications are an effective adjunct therapy for dogs with hemangiosarcoma.

Investigators are assessing the potential for a specific tumor-cell population in canine hemangiosarcoma to sequester drugs within their lysosomes as a novel mechanism of drug resistance.

Researchers will investigate how hemangiosarcoma cells use cholesterol and lipids to promote tumor growth and look at ways to block tumor cells from using these metabolic fuels.

Researchers will investigate how metabolic processes affect tumor growth andchemotherapy resistance in dogs with hemangiosarcoma and ways to block or disrupt these processes.