Researchers are studying the feasibility of an adjunct immunotherapy for large- and giant-breed dogs with osteosarcoma that are not good candidates for cancer surgery or limb amputation.

Researchers will investigate the effectiveness of combining radiation therapy with an immune-stimulating agent to help slow the spread of osteosarcoma, the most common bone tumor in dogs.

Researchers will investigate how a genetic mutation affects treatment success for aggressive osteosarcoma.

Researchers are investigating the effectiveness of a novel immunotherapy to help reduce metastatic disease (cancer spread) and prolong quality of life in dogs with osteosarcoma.

Researchers will investigate the role of a signaling pathway in the progression of bone cancer in dogs and evaluate its potential as a new therapeutic target to help treat this disease.

Researchers are creating tools to estimate fracture risk in giant-breed dogs with osteosarcoma as well as evaluating a novel method to stabilize the affected bone.

SUMMARY: Researchers will study whether a combination of targeted radiation therapy and a novel immune cell homing material can provide body-wide protection against osteosarcoma. THE PROBLEM: Osteosarcoma (OS) is the...