Finding New Strategies to Combat Life-Threatening Glanders
Researchers will investigate how the bacterium Burkholderia mallei which causes glanders, an infectious disease in horses, regulates immune response to persist ininfected animals.
Researchers will investigate how the bacterium Burkholderia mallei which causes glanders, an infectious disease in horses, regulates immune response to persist ininfected animals.
Researchers will explore new techniques to generate stem cells that are more immunologically compatible and less likely to be rejected by the horse's immune system.
Researchers will develop a cryopreservation technique to preserve airway tissue from horses that die of natural diseases with the goal of creating a tissue bank for studying respiratory diseases in horses.
Researchers will compare combinations of antimicrobials to identify the most effective combination for use in a novel, aerosolized, nanoparticle drug delivery system.
Researchers will study subpopulations of immune cells in the blood of horses to discover new strategies to help horses fight off equine herpesvirus infections.
Researchers will investigate a genetic predisposition in Friesian horses to an eye disorder, bilateral corneal stromal loss, which can cause vision loss.
Researchers will evaluate the effects of increased weight loads carried by horses to provide science-based recommendations to the equine industry and address potential welfare concerns.
Using cultured cells, researchers will study how the horse's immune system responds to endotoxins, toxic substances in bacteria responsible for many horse diseases, including gastrointestinal disease and foal sepsis.
Researchers will evaluate the effectiveness of a new surgical suture technique to improve upper airway function in horses with recurrent laryngeal neuropathy, a common upper respiratory disease in horses.
Researchers will improve the quality of the feline genome assembly, an important tool for studying genetic causes and risks associated with diseases in cats.