Heart Failure Drug
University of California, Davis (D20CA-822)
Evaluate the safety and efficacy of the drug clevidipine in dogs with congestive heart failure associated with mitral valve disease. This is a small, preliminary, phase one clinical trial.
Inclusion Criteria: Dogs with myxomatous mitral valve disease and congestive heart failure (fluid present in the lungs).
Enrollment Site: University of California, Davis
Urinary Tract Infections
University of California, Davis (D20CA-044)
Evaluate a novel biotherapeutic for treatment of recurrent and multi-drug resistant urinary tract infections as an alternative to antibiotic treatment.
Inclusion Criteria: Dogs over 3 months old with more than one UTI within the past 12 months or dogs that had a multi-drug resistant bacterial strain identified in the urine.
Enrollment Sites: University of California, Davis Medical Teaching Hospital and Koret School of Veterinary Medicine, Israel
Head & Neck Tumors
Colorado State University (D20CA-312)
Evaluate a novel imaging method to help diagnose the spread of cancer to lymph nodes in malignant head and neck tumors.
Inclusion Criteria: Confirmed diagnosis of head and/or neck tumor, including oral melanoma, oral fibrosarcoma, tonsillar squamous cell carcinoma or salivary carcinoma. Other types of oral tumor types may be eligible on a case-by-case basis.
Enrollment Site: Colorado State University
North Carolina State University (Study ID: D12CA-053)
Find out why some dogs have poor therapeutic response to standard-of-care drugs and find new ways to optimize their therapy.
Inclusion criteria: Dogs diagnosed with proteinuria as a result of kidney disease primarily affecting the glomerulus and that is unlikely to be due to a concurrent disease outside the kidney.
Enrollment sites: North Carolina State University, Iowa State University, Ohio State University and Colorado State University
Immune-Mediated Hemolytic Anemia (IMHA)
Cornell University (Study ID: D19CA-067)
Evaluate the efficacy of a promising, novel treatment for severe blood disorder in dogs.
Inclusion criteria: Dogs diagnosed with intravascular IMHA
Enrollment sites: Cornell University and Cornell University Veterinary Specialists
Anti-Clotting Drugs and Heart Disease
The University of Georgia (Study ID: D16FE-015)
Compare the efficacy of two drugs for preventing recurrent thromboembolism (blood clots) in cats that have experienced and recovered from a prior clot event due to heart disease.
Inclusion criteria: Client-owned cats that have been diagnosed with a thromboembolism due to cardiac disease.
Enrollment sites: Any veterinarian can enroll a cat, but examination by a board-certified veterinary cardiologist is required for inclusion in the study.
The University of Georgia (Study ID: D17EQ-304)
Determine how long infected horses shed Salmonella in their feces and use this new information to improve infection prevention and control.
Inclusion criteria: Horses that are shedding Salmonella (clinically or sub-clinically affected).
Enrollment sites: Throughout the United States and Canada; sample collections kits and instructions provided.
Colorado State University (Study ID: D20EQ-308)
Investigate the efficacy of a novel treatment for ocular surface squamous neoplasia (OSSN), a type of eye cancer in horses.
Inclusion criteria: Confirmed diagnosis of OSSN (or ocular squamous cell carcinoma, SCC)
Enrollment sites: Colorado State University (treatment portion of the study), University of California, Davis (genetic portion of the study)
For More Clinical Trials
Visit the searchable clinical trials database at the AVMA Health Studies Database for a comprehensive list of pet clinical trials in the United States and Canada, including Morris Animal Foundation-funded clinical trials.
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