Clinical Trials
Morris Animal Foundation funds many ongoing clinical trials essential to advancing veterinary medicine. These studies help scientists develop and improve diagnostics, treatments and preventives for a wide range of pet illnesses.
VETERINARIANS AND PET OWNERS: The information below will help you determine if your pet or patient may qualify to enroll in a study. For complete information on each clinical trial, contact the veterinary teaching hospital conducting the study.
DOGS
Ear Infections
University of Pennsylvania, D23CA-801
Assess the efficacy of the antibiotic fosmidomycin to treat canine staphylococcal ear infections.
Inclusion Criteria: Dogs diagnosed with a bacterial infection of both ear canals
Enrollment Site: Matthew W. J. Veterinary Hospital, University of Pennsylvania
Urothelial Carcinoma
North Carolina State University (D19CA-032)
Investigate the validity of a novel diagnostic test for the early detection of urothelial carcinoma, also known as transitional cell carcinoma (UC/TCC), the most common urinary tract cancer in dogs.
Inclusion Criteria: One of six breeds (Scottish terrier, beagle, West Highland white terrier, Shetland sheepdog, American Eskimo dog, Russell/Parson Russell terrier) at high risk of developing a UC/TCC, or a mix related to these breeds.
Enrollment Site: Dogs in the United States. Urine sample collection kit available from North Carolina State University
Urinary Tract Infections
Tufts University (D21CA-083)
Evaluate if three days of the antibiotic amoxicillin is as effective as seven days for the treatment of urinary tract infections in dogs.
Inclusion Criteria: Female and castrated male dogs, 1 to 11 years old, weighing 3-40 kg with urinary tract infections.
Enrollment Sites: Three Massachusetts clinics: Tufts at Tech, Worcester, MA; Tufts VETS, Walpole, MA; and Weston Veterinary Clinic, Weston, MA
Heart Failure Drug
University of California, Davis (D20CA-822)
Evaluate the safety and efficacy of the drug clevidipine in dogs with congestive heart failure associated with mitral valve disease. This is a small, preliminary, phase one clinical trial.
Inclusion Criteria: Dogs with myxomatous mitral valve disease and congestive heart failure (fluid present in the lungs).
Enrollment Site: University of California, Davis
Urinary Tract Infections
University of California, Davis (D20CA-044)
Evaluate a novel biotherapeutic for treatment of recurrent and multi-drug resistant urinary tract infections as an alternative to antibiotic treatment.
Inclusion Criteria: Dogs over 3 months old with more than one UTI within the past 12 months or dogs that had a multi-drug resistant bacterial strain identified in the urine.
Enrollment Sites: University of California, Davis Medical Teaching Hospital and Koret School of Veterinary Medicine, Israel
Immune-Mediated Hemolytic Anemia (IMHA)
Cornell University (Study ID: D19CA-067)
Evaluate the efficacy of a promising, novel treatment for severe blood disorder in dogs.
Inclusion criteria: Dogs diagnosed with intravascular IMHA
Enrollment sites: Cornell University and Cornell University Veterinary Specialists
Weight Management
University of Cambridge, United Kingdom (D22CA-406)
Identify how genetic risk factors and owner behaviors contribute to pet obesity. This study will fill knowledge gaps to improve prevention and treatment of obesity.
Inclusion Criteria: Labrador retrievers
Enrollment Site: Veterinary Hospital of the University of Cambridge
CATS
Clots & Heart Disease
University of California, Davis (D21FE-303)
Investigate the underlying reason why clots form in cats with hypertrophic cardiomyopathy, the most common feline heart disease.
Inclusion Criteria: Healthy cats previously diagnosed with hypertrophic cardiomyopathy.
Enrollment Site: University of California, Davis Teaching Hospital
Fecal Microbial Transplant for Feline Weight Loss
The Ohio State University (D22FE-009)
Assess the efficacy of fecal microbiota transplantation as an adjunctive therapy for weight loss in obese cats.
Inclusion Criteria: Client-owned obese, but otherwise healthy cats
Enrollment Site: The Ohio State University
For More Clinical Trials
Visit the searchable clinical trials database at the AVMA Health Studies Database for a comprehensive list of pet clinical trials in the United States and Canada, including Morris Animal Foundation-funded clinical trials.
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