Clinical Trials

Morris Animal Foundation funds many ongoing clinical trials essential to advancing veterinary medicine and improving the health of animals today and tomorrow. These studies help veterinarians develop and improve new diagnostics, treatments and preventives for pet illnesses, as well as improve the quality of care patients receive.


The information below will help you determine if your pet may qualify to enroll in a study. For complete information on each clinical trial, contact the veterinary teaching hospital conducting the study or consult your veterinarian.

Heart Failure Drug

University of California, Davis (D20CA-822)
Evaluate the safety and efficacy of the drug clevidipine in dogs with congestive heart failure associated with mitral valve disease. This is a small, preliminary, phase one clinical trial.
Inclusion Criteria: Dogs with myxomatous mitral valve disease and congestive heart failure (fluid present in the lungs).
Enrollment Site: University of California, Davis

Urinary Tract Infections

University of California, Davis (D20CA-044)
Evaluate a novel biotherapeutic for treatment of recurrent and multi-drug resistant urinary tract infections as an alternative to antibiotic treatment.
Inclusion Criteria: Dogs over 3 months old with more than one UTI within the past 12 months or dogs that had a multi-drug resistant bacterial strain identified in the urine.
Enrollment Sites: University of California, Davis Medical Teaching Hospital and Koret School of Veterinary Medicine, Israel

Head & Neck Tumors

Colorado State University (D20CA-312)
Evaluate a novel imaging method to help diagnose the spread of cancer to lymph nodes in malignant head and neck tumors.
Inclusion Criteria: Confirmed diagnosis of head and/or neck tumor, including oral melanoma, oral fibrosarcoma, tonsillar squamous cell carcinoma or salivary carcinoma. Other types of oral tumor types may be eligible on a case-by-case basis.
Enrollment Site: Colorado State University

Immune-Mediated Hemolytic Anemia (IMHA)

Cornell University (Study ID: D19CA-067)
Evaluate the efficacy of a promising, novel treatment for severe blood disorder in dogs.
Inclusion criteria: Dogs diagnosed with intravascular IMHA
Enrollment sites: Cornell University and Cornell University Veterinary Specialists


Anti-Clotting Drugs and Heart Disease

The University of Georgia (Study ID: D16FE-015)
Compare the efficacy of two drugs for preventing recurrent thromboembolism (blood clots) in cats that have experienced and recovered from a prior clot event due to heart disease.
Inclusion criteria: Client-owned cats that have been diagnosed with a thromboembolism due to cardiac disease.
Enrollment sites: Any veterinarian can enroll a cat, but examination by a board-certified veterinary cardiologist is required for inclusion in the study.



The University of Georgia (Study ID: D17EQ-304)
Determine how long infected horses shed Salmonella in their feces and use this new information to improve infection prevention and control.
Inclusion criteria: Horses that are shedding Salmonella (clinically or sub-clinically affected).
Enrollment sites: Throughout the United States and Canada; sample collections kits and instructions provided.

Eye Cancer

Colorado State University (Study ID: D20EQ-308)
Investigate the efficacy of a novel treatment for ocular surface squamous neoplasia (OSSN), a type of eye cancer in horses.
Inclusion criteria: Confirmed diagnosis of OSSN (or ocular squamous cell carcinoma, SCC)
Enrollment sites: Colorado State University (treatment portion of the study), University of California, Davis (genetic portion of the study)

For More Clinical Trials

Visit the searchable clinical trials database at the AVMA Health Studies Database for a comprehensive list of pet clinical trials in the United States and Canada, including Morris Animal Foundation-funded clinical trials.

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