Heart Failure Drug
University of California, Davis (D20CA-822)
Evaluate the safety and efficacy of the drug clevidipine in dogs with congestive heart failure associated with mitral valve disease. This is a small, preliminary, phase one clinical trial.
Inclusion Criteria: Dogs with myxomatous mitral valve disease and congestive heart failure (fluid present in the lungs).
Enrollment Site: University of California, Davis
Urinary Tract Infections
University of California, Davis (D20CA-044)
Evaluate a novel biotherapeutic for treatment of recurrent and multi-drug resistant urinary tract infections as an alternative to antibiotic treatment.
Inclusion Criteria: Dogs over 3 months old with more than one UTI within the past 12 months or dogs that had a multi-drug resistant bacterial strain identified in the urine.
Enrollment Sites: University of California, Davis Medical Teaching Hospital and Koret School of Veterinary Medicine, Israel
Head & Neck Tumors
Colorado State University (D20CA-312)
Evaluate a novel imaging method to help diagnose the spread of cancer to lymph nodes in malignant head and neck tumors.
Inclusion Criteria: Confirmed diagnosis of head and/or neck tumor, including oral melanoma, oral fibrosarcoma, tonsillar squamous cell carcinoma or salivary carcinoma. Other types of oral tumor types may be eligible on a case-by-case basis.
Enrollment Site: Colorado State University
North Carolina State University (Study ID: D12CA-053)
Find out why some dogs have poor therapeutic response to standard-of-care drugs and find new ways to optimize their therapy.
Inclusion criteria: Dogs diagnosed with proteinuria as a result of kidney disease primarily affecting the glomerulus and that is unlikely to be due to a concurrent disease outside the kidney.
Enrollment sites: North Carolina State University, Iowa State University, Ohio State University and Colorado State University
Anti-Clotting Drugs and Heart Disease
The University of Georgia (Study ID: D16FE-015)
Compare the efficacy of two drugs for preventing recurrent thromboembolism (blood clots) in cats that have experienced and recovered from a prior clot event due to heart disease.
Inclusion criteria: Client-owned cats that have been diagnosed with a thromboembolism due to cardiac disease.
Enrollment sites: Any veterinarian can enroll a cat, but examination by a board-certified veterinary cardiologist is required for inclusion in the study.
The University of Georgia (Study ID: D17EQ-304)
Determine how long infected horses shed Salmonella in their feces and use this new information to improve infection prevention and control.
Inclusion criteria: Horses that are shedding Salmonella (clinically or sub-clinically affected).
Enrollment sites: Throughout the United States and Canada; sample collections kits and instructions provided.
For More Clinical Trials
Visit the searchable clinical trials database at the AVMA Health Studies Database for a comprehensive list of pet clinical trials in the United States and Canada, including Morris Animal Foundation-funded clinical trials.
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