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Searching for Genetic Risk Factors for Equine Metabolic Syndrome

Equine metabolic syndrome (EMS) is a complex disease, influenced by multiple genetic and metabolic factors. In a previously funded Morris Animal Foundation study, researchers identified more than 180 regions in the horse genome containing genes associated with EMS. In this study, the team will analyze circulating metabolites (substances essential to metabolism and metabolic processes, such as glucose) and gene expression data. Combined analyses will help the team prioritize genetic regions of interest, narrow down the search for candidate genes, and identify risk markers for EMS. Understanding genetic risk factors for EMS will help veterinarians identify animals that can benefit most from management changes and early therapeutic intervention.

Principal Investigator: Molly E. McCue, DVM, PhD, University of Minnesota

Sponsors:

Study ID: D17EQ-019