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Identifying Cancer-Causing Genes for Squamous Cell Carcinomas

Squamous cell carcinoma (SCC) is the most common eye-related cancer in horses. Even with treatment, tumor recurrence is high, with approximately 1 in 5 patients experiencing cancer relapse. Researchers will evaluate three potentially cancer-causing genes associated with SCC. The team will determine if these genes are highly expressed in SCC tumors when compared to normal horse skin. This new information will allow for large-scale investigations on the use of these genes for early cancer detection and as new therapeutic targets to help treat SCC in horses. 

Principal Investigator: Jennifer Luff, VMD, PhD, North Carolina State University

Sponsors:

Study ID: D17EQ-817