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Determining the Long-Term Effects of a Treatment for Chronic Herpesvirus in Cats

Keratitis and conjunctivitis are common ophthalmic conditions that affect many cats. Infection with feline herpesvirus-1 is commonly diagnosed as the cause of these eye problems. Because the virus remains in affected cats for life, they often have recurring infections or develop ocular disease that requires treatment. The antiviral drug cidofovir has been shown to be an effective treatment in cats with clinical signs of acute herpesvirus infection; however, the effects of longer-term use in cats with chronic disease have not been investigated. The long-term application of this drug is known to cause adverse effects in humans and other species. Researchers will evaluate the efficacy and safety of treating cats with chronic herpesvirus infection with topical cidofovir.

D14FE-028
Dr. Cynthia C. Powell, Colorado State University