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Understanding Immune Response to Bacterial Infections in Young Foals

Young foals have immature immune systems, which increases their risk of death due to bacterial infections, such as sepsis, during their first few weeks of life. Dendritic cells play a vital role in initiating and directing the immune response to bacterial infection, and they are particularly important in protecting newborn foals during their first encounter with infectious agents. Using a laboratory model of equine dendritic cells exposed to bacteria, researchers will explore key factors involved in the foal’s immune response to bacterial infections. Findings from this study could help direct the development of novel preventive and therapeutic interventions that would decrease bacterial infections and associated mortality in young foals.

Principal Investigator: Dr. Kelsey A Hart, The University of Georgia

Sponsors:

Study ID: D15EQ-303