Study Identifies a Better Method for Dosing of Chemotherapy Drugs in Dogs
Currently, chemotherapy doses are calculated based on a dog’s body surface area without taking into consideration other physiological factors that could affect drug metabolism.
With funding from Morris Animal Foundation, researchers from Oklahoma State University sought to improve the dosing of chemotherapy drugs by looking at body weight, age and sex, organ weight, and liver function as they relate to drug metabolism. They then developed a method for calculating a safer effective dose of chemotherapeutic drugs that could be incorporated into a software program.
This method for dose calculation will not only benefit dogs, particularly dogs that are larger or smaller than average, but also serve as an aid in the development of new drugs for the treatment of cancer.
Posted by MAF on June 23, 2012. Permalink