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Study Identifies a Better Method for Dosing of Chemotherapy Drugs in Dogs

Currently, chemotherapy doses are calculated based on a dog’s body surface area without taking into consideration other physiological factors that could affect drug metabolism.

With funding from Morris Animal Foundation, researchers from Oklahoma State University sought to improve the dosing of chemotherapy drugs by looking at body weight, age and sex, organ weight, and liver function as they relate to drug metabolism. They then developed a method for calculating a safer effective dose of chemotherapeutic drugs that could be incorporated into a software program.

This method for dose calculation will not only benefit dogs, particularly dogs that are larger or smaller than average, but also serve as an aid in the development of new drugs for the treatment of cancer.

Posted by MAF on June 23, 2012.

Categories: Dog cancer, Dog health, Veterinary research


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Submitted by phyllis at: December 18, 2012
The liver is a major organ that helps in detoxification of the body. Carcinogenic and toxic compounds consumed by dogs pass through it.
Submitted by Nancy Wilson at: July 2, 2012
We were just told the devastating news that our beautiful Golden Bailey Girl has Lymphoma. Can you give us some insight on any new drug that can put her in remission. We found in Lymph nodes in her throat enlarged and it was just confirmed after taking samples from 6 Nodes and sending to the lab. We have had 3 Goldens pass with cancer, however not Lymphoma. We just retired and we are on a very strict budget. Is there anyway you would be able to share your expertise on this. Thank you, Nancy Wilson