Researchers will investigate the role of a genetic mutation found in about one third of dogs diagnosed with hemangiosarcoma, in an effort to find new therapies for dogs affected by this aggressive and highly metastatic cancer.
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Researchers will study the feasibility of using molecules called microRNAs as an early detection tool for hemangiosarcoma, an often-fatal cancer in dogs.
Researchers are exploring if a protein found in some human cancers is also present in hemangiosarcoma tumors, and is a feasible therapy target.
Researchers will use a technique called single-cell RNA sequencing to identify surface markers specific to canine hemangiosarcoma cells as a first step toward the development of a more effective and precise therapy.
Researchers will develop early detection and prevention strategies for dogs with diffuse large B-cell lymphoma.
Researchers will study whether genetic exposures influence onset and age-of-onset for the most commonly acquired urinary incontinence in dogs, urethral sphincter mechanism incompetence.
Researchers will study if the addition of the drug cyproheptadine improves clinical signs and blood parameters in horses receiving the standard-of-care treatment for pituitary pars intermedia dysfunction (Cushing’s Disease).