Researchers will use novel gene-editing tools to correct damaging mutations in heart cells to help advance gene therapies for dilated cardiomyopathy, a common canine heart disease.
Researchers will screen genomes of several strains of bacteria causing leptospirosis, a potentially fatal disease in dogs, to help identify vaccine candidates and improve protection against infections.
Researchers will conduct a clinical trial to see if three days of the antibiotic amoxicillin is as effective as seven days for the treatment of urinary tract infections in dogs.
Researchers will explore the potential of gene therapy (reprogramming of cells already present in the body through the transfer of genes) as a new strategy to treat osteoarthritis in dogs.
Researchers will evaluate several drugs in a novel three-dimensional culture model to gauge their potential as new treatments for pituitary-dependent hyperadrenocorticism, also known as Cushing’s disease.
Researchers will investigate the cat-and-mouse game between the dog’s immune response and canine parvovirus, an infectious gastrointestinal illness of puppies and young dogs.
Researchers will investigate a novel nanoparticle system to deliver chemotherapy drugs directly to osteosarcoma tumors, the most common bone cancer in dogs.
Researchers will evaluate a novel probiotic’s potential as a safe and effective treatment for pyoderma, a bacterial skin infection often caused by Staphylococcus bacteria.
Researchers will look at how coinfections of two types of bacteria work together in dogs with urinary tract infections and use this new information to improve treatment