Researchers will investigate the potential of a platelet-derived product called platelet lysate as a non-antibiotic option to treat persistent infections in horses.
Researchers will use systems biology, a comprehensive way of looking at multiple factors involved in complex diseases, to study equine metabolic syndrome, a metabolic and hormonal disorder and the most common cause of laminitis in horses.
Researchers will determine if stem cells from horse bone marrow can reduce bacterial biofilm formation and associated inflammation that cause treatment failure and tissue damage in horses with orthopedic infections.
Researchers will quantify how horses adapt muscle function and limb and upper body movements to cope with lameness, providing a greater understanding of clinical signs that can guide assessment and earlier intervention.
Researchers will collect preliminary bench-top data on a novel oncolytic therapy for equine sarcoid tumors using a genetically modified virus that infects and breaks down cancer cells but not normal cells.
Researchers will investigate the effect of a commonly administered intravenous fluid, called hydroxyethyl starch, in horses undergoing surgery for colic, specifically looking at microcirculation, blood pressure and cardiac output.