Researchers will study the feasibility of using molecules called microRNAs as an early detection tool for hemangiosarcoma, an often-fatal cancer in dogs.

Researchers will develop statistical breeding models to help reduce hemangiosarcoma incidence in dog breeds.

Researchers will study how inflammatory bowel disease progresses into feline intestinal lymphoma, a much-needed step toward the development of better preventives, diagnostics and therapies.

Researchers will study how to block an immune protein associated with the accelerated spread of osteosarcoma in dogs.

Cancer researchers have been improving treatments for different cancers by identifying genetic variants (errors in the genetic code) in the tumors, and by identifying or developing new drugs that can...

Researchers will develop early detection and prevention strategies for dogs with diffuse large B-cell lymphoma.

Researchers will use state-of-the-art gene editing techniques to identify genes that influence growth and progression of oral squamous cell carcinoma tumors in cats.

Researchers will search for new therapy targets for hemangiosarcoma in dogs to inform the development of much-needed therapies and preventives for this deadly cancer.

Researchers will study the cellular landscape of soft-tissue sarcomas in dogs to identify novel therapy targets.    

SUMMARY: Researchers will evaluate an innovative approach using engineered intracellular bacteria called quasiorganelles as a platform for the intracellular delivery of proteins to histiocytic sarcoma cells and surrounding immune cells in the local tumor environment. This proteins have been selected to suppress cancer growth and stimulate the immune system for the purpose of eliminating cancer cells.