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Testing a Rescue Therapy for Horses with Acute Respiratory Distress

The prevalence of chronic airway disease is estimated to be 14 to 80 percent in individual horse populations throughout the United States and Europe, accounting for respiratory disease as the second cause of retirement in horses. Recurrent airway obstruction (RAO), an asthmalike disease, has been cited as one of the most frequent respiratory diseases in horses. Intravenous administration of magnesium sulfate solution is used to treat acute asthma attacks in people. Researchers will determine whether magnesium sulfate therapy can relax airway smooth muscle and improve ventilation in horses that experience seasonal RAO. This study will provide new information on the safety and efficacy of this novel and inexpensive therapy for managing horses with acute respiratory distress.

Principal Investigator: Dr. Jacquelyn E Bowser, Mississippi State University

Sponsors:

Study ID: D15EQ-803