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Improving Immunotherapy for Allergy Treatment in Horses

Horses are often affected by allergic diseases, for which allergen-specific immunotherapy (ASIT) is the only causative treatment. However, in its present form ASIT often leads to only partial improvement of clinical signs and it requires several injections over many years. In addition, severe side effects can occur. Researchers will evaluate how to enhance the immune cells’ recognition and uptake of recombinant allergens and thereby improve the treatment of allergies in horses. The information will also help improve allergy treatment in other species, such as dogs and cats, and the techniques used may also be useful in improving the efficacy of vaccines against infectious diseases. 

Principal Investigator: Dr. Eliane Marti, University of Berne, Pilot Study

Sponsor:

Study ID: D14EQ-811