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Identifying Ways to Make Bone Tumors Less Aggressive

Researchers theorize that tumors with inactive tumor suppressor protein RB are highly aggressive, and those with active RB are less aggressive. Drugs that alter the structure and organization of DNA appear to restore RB function. This study assesses whether these drugs can convert highly aggressive canine bone tumors into less aggressive canine tumors that have a better prognosis.

D13CA-032
Dr. Jaime F. Modiano, University of Minnesota

Co-sponsors: Anonymous