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Finding new therapy targets for mast cell tumors

Summary: Researchers will identify new therapy targets for malignant mast cell tumors, a common and aggressive cancer in dogs.

Description: Mast cell tumors account for up to 20 percent of all skin cancers in dogs, but little is known about the underlying biological mechanisms responsible for tumor growth. Researchers will use recent advances in DNA technologies to catalog genetic mutations of canine mast cell tumors. This catalog will guide a broader analysis of key cancer-driving mutations and will help identify potential new therapy targets for this common canine cancer. 


INVESTIGATOR: Dr. Matthew Breen, North Carolina State University

Baird Medical Trust in memory of Stephanie and Jerry Katz
Flat-Coated Retriever Foundation
Pug Dog of America
Anonymous, in memory of Grover