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Evaluating Drugs That Inhibit Oral Cancer Growth

Feline oral squamous cell carcinoma is the most common type of mouth tumor in cats. It is an extremely aggressive cancer that destroys the tissue in the cat's mouth and frequently invades the bone. There is no effective treatment and cats with this cancer survive an average of only two months. An important aspect of this disease is its invasion of the bone, but this process isn't understood. The researchers believe that bone destruction encourages tumor growth. They will use in vitro techniques to evaluate the effectiveness of two drugs in inhibiting bone destruction and cancer growth. This study will lay the groundwork for important clinical trials of these drugs.