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Identifying Breed Differences in Insulin Sensitivity in Horses

Equine metabolic syndrome (EMS) is characterized by high concentrations of insulin in the blood, which can predispose horses to developing laminitis. Certain breeds appear to be more susceptible to EMS. Preliminary data demonstrate that breeds differ in their response to insulin and in the effectiveness of insulin in controlling blood glucose levels (insulin sensitivity). Researchers will examine the metabolic characteristics of muscle and fat tissue in different breeds (Quarter Horses, Arabians, Tennessee Walking Horses and Welsh ponies) in relation to insulin sensitivity. Identifying unique breed-related differences in metabolism will help determine horses at-risk for EMS. 

Principal Investigator: Dr. Jane M. Manfredi, Michigan State University, Fellowship Training Grant

Sponsor: 

Study ID: D14EQ-401