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Since our founding in 1948, Morris Animal Foundation has funded hundreds of health research studies to protect, treat and cure the world's companion animals and wildlife.
Our studies have led to major advances in veterinary care, including vaccines and other preventions, diagnostic tools and new therapies for the diseases and health conditions that threaten the lives of the animals we love. Search our completed study database by species and/or disease to learn more about how our work has given animals longer, healthier lives.
Category
D05EQ-618: Pharmakokinetic and Pharmacodynamic Modeling of Oral Dexamethasone Administered to Heatlhy Horses
principal investigator: Amanda Sherck, student, Kansas State University
Project Mentor: Elizabeth Davis, DVM, PhD
completed
Year: 1 of 1. $0
Corticosteroids, such as dexamethasone, have an anti-inflammatory effect and can be vital when treating diseases such as heaves. Dexamethasone is often administered orally however there has not been any research to document its success when administered in this manner versus intravenously. This study looked at the absorption of Dexamethasone when given orally as compared to when it is given intravenously. They found that the orally administered drug resulted in reduced serum cortisol concentrations indicating a physiological response.
Amanda says, "Due to my experiences with the summer research program sponsored by Morris Animal Foundation I have developed an interest in research and am now considering graduate research as an option."
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