Archive for the ‘Dog’ Category

Searching for the next top dog

Tuesday, September 15th, 2009

Photo courtesy of Wendy Dickie Fine Eye Photography

Your dog could be a top model. MAF has teamed with Orvis and Eukanuba to help find a cure for canine cancer through Orvis’s annual photo contest. Submit photos of your favorite canine at http://www.orvis.com/coverdog by Jan. 24, 2010. The winning photograph will grace the cover of the fall 2010 Orvis Dog Book, and the winning photographer will win a $500 Orvis gift card. Vote for your favorite dog for just $1 per vote, with all voting proceeds going toward MAF’s Canine Cancer Campaign. Orvis and Eukanuba, together, will match your contribution up to $30,000. So, every vote you cast becomes $2 toward research to prevent, treat and cure cancer.

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Additional Therapeutic Option for Controlling Seizures

Monday, September 14th, 2009

Photo courtesy of Wendy Dickie Fine Eye Photography

Study Results:

Primary, or idiopathic, epilepsy, a common disorder in dogs, is characterized by recurrent seizures with no known cause. Antiseizure medications are most often used to treat this disease; however, up to 30 percent of dogs are resistant to the medications and less than half of all epileptic dogs remain seizure-free without experiencing drug-related side effects. Scientists at North Carolina State University evaluated and validated a new antiepileptic drug, levetiracetam, as an add-on drug to be used in conjunction with today’s conventional treatment with phenobarbital and potassium bromide. Based on the results of the study, levetiracetam is a safe add-on therapy in epileptic dogs when treatment with phenobarbital and potassium bromide has failed to control seizures. (Do3CA-124)

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Insight Into Chemotherapy Resistance

Monday, September 14th, 2009

Photo courtesy of Wendy Dickie Fine Eye Photography

Study Results:

Cancer is the leading cause of disease-related death in dogs, which is why Morris Animal Foundation has invested considerable resources into understanding this group of diseases and developing more effective treatments. Cancer develops when genes that control the balance of cell division and survival cease to function normally and cause a cell to become malignant. One of these genes is called PTEN. The protein product of this gene generally restrains cell division, in part by controlling p21, another protein. Scientists at the University of Minnesota and the University of California–Davis found that using compounds to lower the levels of p21 in some tumors decreased resistance to conventional chemotherapy drugs. They also concluded that chemotherapy resistance is sometimes unrelated to abnormalities of PTEN, though it is often associated with elevated p21 levels. The results from this MAF-funded project allowed the investigators to justify efforts to move these compounds to the next step of clinical development. (D06CA-065)

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Signs Your Dog May Have Arthritis*

Thursday, August 13th, 2009

If you’re a dog owner, you’re conscientious about looking after your pet’s diet and making sure he or she gets plenty of exercise. But some days, your happy-go-lucky friend may seem different, and you’re not sure why. Watch for these early-warning signs of arthritis in your canine companion:

  • Favoring a limb
  • Difficulty sitting or standing
  • Sleeping more than usual
  • Seeming to have stiff or sore joints
  • Reluctance to jump, run or climb stairs
  • Weight gain
  • Decreased activity or less interest in play
  • Barking or whimpering when touched
  • A personality change that involves resisting touch
  • Seeming less alert

*According to the Arthritis Foundation and PetWellbeing.com

Please consult your pet’s veterinarian at the earliest signs of these or any other unusual changes in behavior. Your dog deserves to live a long, healthy and active life.

AnimalNews and Enews keep you up to date on the latest Morris Animal Foundation research and success stories. Click here to subscribe.

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Orvis Cover Dog Photo Contest Supports MAF

Wednesday, July 29th, 2009

Orvis and Eukanuba Dog Food have teamed up with The Morris Animal Foundation to help find a cure for canine cancer. With your help, we can save countless dogs from suffering and premature death. Orvis and Eukanuba, together, will match your tax-deductible contribution to the Canine Cancer Campaign up to a total of $30,000. So, every dollar you donate becomes $2 for the Canine Cancer Campaign.

Click here to enter your dog in the contest and support canine cancer research!

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MAF Successful Outcome

Wednesday, July 22nd, 2009

Great Dane

Identifying Genes that May Improve Bone Cancer Treatment: Large and giant dog breeds have a high risk for osteosarcoma, a highly aggressive bone cancer that spreads (metastasizes) to the organs. Despite aggressive treatment with surgery followed by chemotherapy, most dogs survive less than one year after diagnosis because the cancer recurs in other bones or organs, particularly the lungs. Scientists from Colorado State University are studying the biological mechanisms (prognostic biomarkers) that contribute to the disease’s spread and resistance to standard therapy. This would help veterinary researchers identify common genetic features that contribute to the disease’s ability to spread, develop tailored therapeutic approaches and identify new drug targets—all of which would help veterinarians and owners make more successful treatment decisions for dogs that are fighting osteosarcoma. To date, they have identified and validated 11 genes that could serve as biomarkers to determine whether a patient is likely to respond to standard therapies.

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AKC creates canine health and welfare advisory panel

Monday, July 20th, 2009

DVM NEWSMAGAZINE

New York — The American Kennel Club (AKC) organized a new AKC Canine Health and Welfare Advisory Panel.
The panel’s goal will be “to provide factual and impartial information by creating a forum for proactive discourse based on scientific and ethical concerns,” according to a media release.

Click here to read the full article.

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Meisha’s Hope Bandanna Now Available!

Thursday, July 16th, 2009

For a donation of $10.00 or more to the Meisha’s Hope AIHA/IMHA Fund #338 at Morris Animal Foundation, you can receive a Meisha’s Hope Bandanna and help in the fight against AIHA/IMHA at the same time. Click here for more information.

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Zelda: A Cancer Survivor’s Tale

Monday, June 29th, 2009
tough times never last...tough people do

tough times never last...tough people do

This Bulldog’s Tougher than Cancer

Truly, America loves its celebrities. Even ones with wet noses and four legs. Asked to name a few, you might list Rin Tin Tin and Lassie. Maybe Checkers or Benji. Oh yes, and Zelda.

Who’s Zelda? A canine star for today’s generation. A doggie diva who has made the talk show rounds, appearing on Oprah, Good Morning America, the Today Show, Martha Stewart, and more. A survivor who has outlived cancer, not to mention her own life expectancy.

This sassy English Bulldog rose to fame as the star of Zelda Wisdom, a wildly successful business venture by Zelda’s owner, Carol Gardner. Combining Zelda’s costumed poses with Gardner’s funny, heartwarming captions, the company designs greeting cards, calendars, books, figurines and dozens of other items. “I think there have been close to 200 Zelda products,” Gardner exclaims, “It’s pretty amazing.”

Zelda’s high-profile image has given her the opportunity to help raise awareness for worthy causes such as the Delta Society and Pet Peace of Mind, both organizations that promote the power of animals to heal human suffering.

In September 2008, Gardner had a lunch date with a representative from the Morris Animal Foundation, well known for its Canine Cancer Campaign. She recalls that Steve Strand, who is very interested in pet insurance as, CFO of Pets Best Insurance, had urged the two to get together. “He said ‘you’ve just got to meet them because the work they’re doing on cancer is extraordinary.’ The irony of it was that Zelda didn’t have cancer at the time.”

(more…)

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More Effective Drug Dosing for Allergic Skin Disease in Dogs

Friday, June 26th, 2009

dog

Study results:

Atopic dermatitis is a common allergic skin disease in dogs and humans. Antihistamines are commonly prescribed treatments, but there is a need to scientifically determine the optimal doses. With MAF funding, researchers validated the commonly used antihistamine, hydroxyzine, and determined that the optimal dose is twice daily rather than the current three times a day prescription. They also discovered that when hydroxyzine is administered orally or intravenously, the drug breaks down into its simpler form (cetirizine), and this simpler form is responsible for the actual antihistamine effect. Researchers now want to look at cetirizine for treating atopic dermatitis. (D07CA-029)

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