Archive for November, 2009

Better nutrition for birds

Monday, November 30th, 2009

birdsMorris Animal Foundation has funded avian studies for nearly 25 years, and much of that research has gone into improving nutrition for companion birds. A few highlights are below.

All birds require vitamin A to maintain the functionality of their vision, the lining of the mouth, the esophagus and other body surfaces. Nutritionally, though, vitamin A is the most challenging of the vitamins because it is the most likely vitamin to be either deficient or excessive in the diets of companion birds. Both deficiencies and excesses of vitamin A result in changes in behavior, and at toxic levels, vitamin A causes birds to be hyperexcitable and very vocal. A Foundation-funded study in the late 1990s determined the optimum level of vitamin A in the diet of cockatiels. Researchers learned that a level of 2,000 IU per kilogram of dietary intake gives optimum health. The knowledge led to better diets for these birds.

Vitamin D3 and calcium are also essential nutrients for parrots, and excesses and deficiencies of these nutrients commonly cause disease. A second Foundation-funded study examined avian diets containing various concentrations of vitamin D3 and calcium to determine optimal amounts for growth and reproduction in parrots. Before that study, nothing was known about these two key elements. This revolutionary study in the late 1990s showed that in budgies (parakeets), one of most commonly kept birds in the United States, safe and adequate levels of dietary calcium were less than half of the standard. As a result, commercial diets prepared for them at that time contained a toxic level of calcium. Fortunately, the vitamin D3 concentrations found in commercial pet diets were deemed safe for budgerigars. With the information determined by this study, new diets were formulated for these birds to help increase their life span and quality of life.

Foundation-funded research into optimizing bird nutrition continues today. A current study is reviewing the diets of wild species to learn how to improve diets of captive birds, such as macaws, Amazon parrots, cockatoos and other large psittacine birds. Hand-reared chicks often suffer from nutritional deficiencies, aspiration due to the finely ground texture of the feed and slow digestion, which causes dehydration and malnutrition. With Foundation funding, researchers are analyzing the nutrient content of the diets of wild chicks living in Peru, Mexico, Brazil and Costa Rica. They will use these measurements to formulate new hand-rearing diets for captive parrot chicks. If the new formulas improve nutrition and reduce acute and chronic health problems, the research would revolutionize hand-feeding and improve the health of companion parrots worldwide.

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Better Evaluation of Suspected Lymphoma Cause

Wednesday, November 18th, 2009

boxerStudy Results:

Lymphoma is one of the most common cancers in dogs. Its cause is unknown, but genetic, environmental and infectious-disease factors may play roles in the cancer’s development. Previous research suggested a link between lymphoma and infections with hemoplasmas-bacteria that adhere to red blood cells and can persist in a dog’s blood without causing clinical signs of disease. The goal of this study was to determine whether dogs with untreated lymphoma have a higher prevalence of hemoplasma infection than dogs with untreated mast cell tumors or sarcomas.

Scientists collected blood samples from dogs with soft-tissue sarcoma, lymphoma and mast cell tumors that had not been treated with chemotherapy. The researchers detected hemoplasmas in 5 percent of the dogs tested and identified the species of infecting hemoplasma for each positive sample. The frequency of hemoplasma infection did not differ in dogs with lymphoma compared with the frequency in dogs with soft-tissue sarcoma or mast cell tumors. Because their previous studies showed a higher frequency of hemoplasma infections in dogs with lymphoma that were being treated with chemotherapy, the researchers hypothesize that chemotherapy may contribute to increased hemoplasmas or may predispose a dog to infection with these organisms. They now plan to evaluate the infected dogs to determine whether subsequent chemotherapy was associated with unexpected complications (such as hemolytic anemia) in these dogs. (D08CA-087)

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MAF’s Cat Campaign Celebrates a Year of Better Cat Health

Tuesday, November 17th, 2009

Morris Animal Foundation’s Happy Healthy Cat Campaign celebrates its first anniversary today.

We’re happy to report that the Foundation has made significant progress toward improving cat health. In 2009, we began funding year one of three Helping Shelters Help Cats studies that will ultimately help cats stay healthy and stress free until they are adopted. Already, the studies suggest that stressful conditions dramatically increase the likelihood of upper respiratory infection, but simple housing modifications reduce stress and the spread of infection-making the difference between life and death for a shelter cat.

In 2010, the Foundation will launch a major feline genomic research project that will help researchers worldwide prevent and treat the most serious disease affecting cats today.

Please honor the cats who’ve made a difference in your life with a gift to improve feline health. Visit www.Research4Cats.org. Every dollar you give will be matched up to $500,000-that means $1 million to help save cats-to help fund the next two years of research.

Thank you for helping cats enjoy longer, healthier lives!

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When the Common Cold Becomes Deadly

Monday, November 16th, 2009

HHCC

When the Common Cold Becomes Deadly, Foundation-Funded Researcher Provides Hope

By Heather Grimshaw

Seeing cats in shelter cages is difficult for most people. Seeing sick cats in cages—and knowing that their illness is preventable yet may lead to euthanization—propelled Dr. Kate Hurley into action. A Morris Animal Foundation–funded veterinarian who specializes in shelter medicine, Hurley works tirelessly to improve shelter environments so cats have a chance to thrive.

“You can imagine that entering a shelter is, for some cats, the hardest thing they will ever have to face,” explains Hurley. “Either they were stray or they were out in a field somewhere hunting in the grass and out in the sunshine, and all of a sudden they’re in a stainless steel box about two feet by two feet in size. There are weird smells, they have nowhere to hide, there’s the sound of doors clanging shut, there might be dogs barking and they need to show the kind of friendly, outgoing behavior that is going to make an adopter fall in love with them and take them home. What a challenge for an animal.”

Hurley, who started her career as an animal control officer continues to work on behalf of cats as director of the Koret Shelter Medicine Program at the University of California–Davis School of Veterinary Medicine. With Foundation funding, Hurley has embarked on a series of projects to assess whether controlling stress in shelters will diminish the incidence of feline upper respiratory infections (URIs). So far studies suggest that stressful conditions dramatically increase the likelihood that cats will develop colds, or URI. And, due to fear of spread, these cats are often euthanized by cash-strapped shelters.

On a national level, statistics of sick cats in shelters are heartbreaking. An estimated 4 million cats pass through United States shelters, and URI is among the top reasons for euthanasia.

Yet, thanks to Hurley, there is light at the end of this very dark tunnel.

Her Foundation-funded national effort to assess shelter environments—including disease incidence, cage layout and sanitation methods—has already resulted in a significant reduction in reported infection.

“Our hope is that we’re going to find something that not only helps cats stay healthy but also helps them get out of shelters alive,” she adds.

Her research also shows that prevalence of feline URI varies wildly across the country.

“We’re talking about some shelters where 80 to 90 percent of the cats get sick in comparison to shelters where 5 percent or less of the cats get sick,” she says.

This vast variance indicates that environmental factors play a significant role in disease prevention and spread. Hurley hopes to answer the question of why there are such differences.

Environmental risk factors explain some of the massive variation and, so far, shelters with the lowest URI rates seem to be those with high-quality housing for cats.

Hurley’s current study, one of three Helping Shelters Help Cats studies funded through the Foundation’s Happy Healthy Cat Campaign, builds on her previous results and will assess the impact of multi-compartmental cages (with hiding spots and separate feeding and elimination areas) on feline URI and well-being. While these studies focus on shelters, findings are relevant to all pets.

“Shelter research is applicable to veterinary clinics, catteries and kennels when it comes to identifying and establishing methods for reducing URI and stress for animals,” Hurley says.

Watch video of Hurley talking about her shelter work.

Every dollar you donate to Helping Shelters will be matched by an anonymous donor. Learn more about the shelter studies as well as symptoms of upper respiratory infection and support this critical research at http://www.research4cats.org/health-research/helping-shelters-help-cats/.

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Canine Influenza Virus

Wednesday, November 11th, 2009

New Research Funding Looks to Stop Spread of Canine Influenza Virus


Morris Animal Foundation is funding a new three-year study on Canine Influenza Virus (CIV). Led by Dr. Gabriele Landolt of Colorado State University, the project will help shelters develop effective testing and control methods to limit the effects of this disease in communities nationwide.

Commonly known as canine flu, CIV causes a great deal of pain and suffering in dogs. It spreads through coughing, sneezing and close contact in closed environments, which makes canine flu particularly damaging to dogs in shelters. Many shelters find it nearly impossible to rid their facilities of the disease once it is introduced. It can also affect pet dogs that spend time in boarding kennels and doggie daycare. Read more about symptoms.

Researchers will learn more about how canine flu spreads among shelter dogs and will also determine whether there is a reliable “patient-side” test that could detect the virus during a dog’s intake exam at a shelter. This would allow shelter managers to quarantine affected dogs and keep the virus from spreading to healthy animals. The information learned could also help promote the use of a vaccine for this emerging and common virus.

The study will feature ASPCA partners in Sacramento, Austin, Tampa, Charleston, New York and Colorado Springs. Dr. Miranda Spindel, ASPCA director of veterinary outreach, will be working with Dr. Landolt on the study.

First identified as a respiratory pathogen in 2004, CIV has spread widely among dogs in the United States. Morris Animal Foundation began funding research into disease prevention and transmission in 2005 and has provided nearly half a million dollars in research funding to study this canine health issue.

Read about additional canine influenza research the Foundation is funding at the University of Florida and Colorado State University.

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Veterinary Technician Pursues Interest in Veterinary Neurology

Thursday, November 5th, 2009
Photo cutline: Stephanie Gilliam, RVT, CCPR, with one of her favorite patients. Susan, a pointer, had spinal surgery nearly two years ago. She never regained feeling in her back http://www.morrisanimalfoundation.org/blog/wp-admin/edit.phplegs, but, as Gilliam says, "She is still just as happy as can be!"
Stephanie Gilliam, RVT, CCPR, with one of her favorite patients. Susan, a pointer, had spinal surgery nearly two years ago. She never regained feeling in her back legs, but, as Gilliam says, “She is still just as happy as can be!”

Veterinary Technicians-Supporting the Advancement of Veterinary Research One Patient at a Time

Stephanie Gilliam pursues her interest in veterinary neurology

Working in the neurology/neurosurgery department at a veterinary teaching hospital can be emotionally difficult-not every patient walks away. Yet recoveries make every challenge worthwhile for Stephanie Gilliam, a registered veterinary technician (RVT) who works as the neurology/neurosurgery technician at the University of Missouri Veterinary Medical Teaching Hospital.

“A lot of our patients are completely paralyzed or close to it when they come to us,” explains Gilliam, who is certified in canine physical rehabilitation. “The day we see them move their legs or walk on their own is the greatest. That is why I do what I do.”

Gilliam, who has worked at the university-in a research laboratory with Morris Animal Foundation (MAF)-funded researchers and at the teaching hospital-collaborates with veterinary medical students and neurology specialists to treat a variety of ailments that affect the nervous system.

The most common diseases are intervertebral disk disease and seizures, says Gilliam, who adds, “Most of these patients recover just fine and end up living normal happy lives.”

Ever since she was a kid, Gilliam knew she wanted to work with animals, but a job with Dr. Joe Kornegay, a veterinary neurologist who specializes in muscular dystrophy research, stoked her interest in neurology research.

“That is when I started to love neurology,” she says. “My favorite part of it is the surgery cases, but the medical cases are interesting as well. Who doesn’t think that brain surgery is interesting?”

Hands-on experience has given Gilliam a keen sense of respect for the important role research plays in the health and wellness of animals and, by extension, people.

“Our patients are living longer, happier lives because of research,” she says. “We are constantly finding new treatments, surgical procedures, etc., to help animals live longer lives. Research is essential to both human and veterinary medicine.”

At the teaching hospital, researchers are studying a canine disease called degenerative myelopathy, a spontaneously occurring spinal cord disorder in adult dogs. The Foundation has funded at least 25 animal health studies at the university, including a Veterinary Student Scholar project that addressed this disorder.

“Dr. Joan Coates, a veterinary neurologist [and a team of researchers, including MAF-funded Veterinary Student Scholar Rachael Cohen] discovered the gene that they believe to be responsible for degenerative myelopathy,” says Gilliam.

To read more about this MAF-funded Veterinary Student Scholar study, titled “Risk Factors for Spinal Cord Injury,” visit the MAF Web site. Information about the Veterinary Student Scholar program is also posted online.

Dr. Coates’s study was originally funded by the AKC Canine Health Foundation.

Recent findings from the university indicate that the gene believed to cause degenerative myelopathy also causes Lou Gehrig’s disease in people.

“We are still working to learn more about this disease so that we can hopefully help the dogs as well as the people living with it,” Gilliam adds.

While Gilliam loves her work, she recognizes limitations to what medical professionals can accomplish. And, as an animal lover, that reality is a frequent source of frustration.

“The most challenging aspect [of my job] is the fact that we can’t ‘cure’ every patient,” she says.

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Rare Births of Captive Clouded Leopard Cubs

Thursday, November 5th, 2009

Clouded Leopard

MAF funding may lead to rare births of captive clouded leopard cubs

by Heather Grimshaw

From AnimalNews 9.1

The clouded leopard population is in dire straits. Only 78 cats remain in the North American Clouded Leopard Species Survival conservation program. Because of various factors—including a high rate of males killing females and reproductive issues—their numbers continue to fall.

But Morris Animal Foundation (MAF)–funded efforts to develop hormone protocols for artificial insemination show promise—and soon, a baby may be on the way.

With MAF funding, Dr. Katey Pelican and Dr. JoGayle Howard at the Smithsonian Institution learned that ovulation cycles in clouded leopards differ from those of other cats. About 50 percent of clouded leopards ovulate spontaneously after estrus (heat) in contrast to ovulation induced only by breeding (typical for most cats). After studying hormone prototocols in 38 animals, several clouded leopards were inseminated using the optimum hormones.

The collaborating zoos fed female clouded leopards meatballs injected with “whopping” levels of progesterone to shut the ovaries down. Then injections of ovarian-stimulating hormones brought the cats into heat so the team could schedule the insemination with the synchronized ovulations. If all goes well, the resulting babies will be the first clouded leopards born in the United States since 2003.

Mystifying creatures

Described as little acrobats that swing on the tiniest limbs, clouded leopards have enormous paws and dart down trees vertically. Males, at about 50 pounds, are almost twice the size of females and have the longest canine teeth of any cat species.

Most clouded leopards in the United States are close cousins, if not siblings, which poses a genetic diversity quagmire. To address the problem, a consortium of conservation agencies began a breeding and research program in Thailand. However, environmental stress, confined cages, inconsistent keepers and limited nesting boxes in this country stack the deck against mating. Most attempts to pair clouded leopards result in fatalities, though Pelican notes that once cats pair up, they breed regularly.


Better breeding in the works

Pelican and Howard broadened the research to include ways to reduce stress and enrich gene pools naturally. They discovered that introducing males to females while the male is still young (about 1 year old) and hasn’t hit puberty reduces its aggression toward potential mates. The team also brought six cubs from Thailand, where 39 clouded leopards have been born since 2002. Cubs from this area are genetically valuable because they are not closely related to the North American cats and will help diversify the gene pool. The goal is to bring the population total to 120 cats in North America.

Support wildlife health research. Donate today.

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Web Exclusive Discusses Why Wildlife Health Matters

Monday, November 2nd, 2009

Web Exclusive Discusses Why Wildlife Health Matters, Features Joan Embery

Morris Animal Foundation Videos Illustrate Connection Between Humans, Pets and Wildlife

Wildlife animal health affects our world in a myriad of ways. To connect the dots between wild habitats and your backyard, Morris Animal Foundation created an online wildlife health exclusive, which features veterinary professionals, animal health advocate Joan Embery and adorable examples of wildlife. The exclusive (http://www.MorrisAnimalFoundation.org/wildlifeweb/) has six short videos that illustrate how wildlife animals affect you and your pets, articles with additional information and a list of helpful resources.

Morris Animal Foundation, a Denver-based nonprofit, is a world leader in funding wildlife health research that helps animals escape extinction, extend life span and repopulate.

Foundation executives and veterinarians Patricia Olson and Wayne Jensen talk about the importance of establishing medical markers for wildlife and ensuring survival of unique and ecologically valuable species. They are joined online by University of California-Davis researchers who are using Foundation funding to study seals, sea otters and endangered Santa Catalina Island foxes.

Embery, who is known for her appearances on the “Johnny Carson Show,” celebrates many species on her Pillsbury Ranch in San Diego and introduces Yoda, a fennec fox that is sure to steal hearts. She talks about the concept of “one health” and the importance of wildlife research and conservation efforts.

“Increasingly, as we crowd this earth, we will be affected more and more by wildlife diseases,” says Dr. Barbara Wolfe, DVM, PhD. Wolfe is a former chair of the Foundation’s Wildlife Scientific Advisory Board, which reviews hundreds of Morris Animal Foundation grant submissions from around the world.

Learn more at www.MorrisAnimalFoundation.org/wildlifeweb.

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