Archive for June, 2009

Zelda: A Cancer Survivor’s Tale

Monday, June 29th, 2009
tough times never last...tough people do

tough times never last...tough people do

This Bulldog’s Tougher than Cancer

Truly, America loves its celebrities. Even ones with wet noses and four legs. Asked to name a few, you might list Rin Tin Tin and Lassie. Maybe Checkers or Benji. Oh yes, and Zelda.

Who’s Zelda? A canine star for today’s generation. A doggie diva who has made the talk show rounds, appearing on Oprah, Good Morning America, the Today Show, Martha Stewart, and more. A survivor who has outlived cancer, not to mention her own life expectancy.

This sassy English Bulldog rose to fame as the star of Zelda Wisdom, a wildly successful business venture by Zelda’s owner, Carol Gardner. Combining Zelda’s costumed poses with Gardner’s funny, heartwarming captions, the company designs greeting cards, calendars, books, figurines and dozens of other items. “I think there have been close to 200 Zelda products,” Gardner exclaims, “It’s pretty amazing.”

Zelda’s high-profile image has given her the opportunity to help raise awareness for worthy causes such as the Delta Society and Pet Peace of Mind, both organizations that promote the power of animals to heal human suffering.

In September 2008, Gardner had a lunch date with a representative from the Morris Animal Foundation, well known for its Canine Cancer Campaign. She recalls that Steve Strand, who is very interested in pet insurance as, CFO of Pets Best Insurance, had urged the two to get together. “He said ‘you’ve just got to meet them because the work they’re doing on cancer is extraordinary.’ The irony of it was that Zelda didn’t have cancer at the time.”

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New Knowledge to Fight West Nile Virus in Raptors

Friday, June 26th, 2009

red-tailed-hawk

Study results:

West Nile virus (WNV) infects the eyes of red-tailed hawks, causing vision impairment that may lead to total blindness. With funding from MAF, scientists now have a better understanding of how the virus targets and damages the retina, and they were also able to identify different types of lesions that they believe represent various stages of WNV disease. This valuable knowledge will help with early diagnosis, determine severity of disease and provide for better treatments for red-tailed hawks and other related raptors. This First Award grant also helped a newly appointed faculty member establish his lab and research program. (D07ZO-303)

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Better Future Vaccines for Horses

Friday, June 26th, 2009

horse

Study results:

Bacteria and viruses can cause many kinds of infection in horses. Specific parts of a bacterium’s or virus’s structure can also stimulate the body to fight a disease or activate cells — allowing vaccines to be effective. MAF funding helped researchers determine how white blood cells in horses use specific, and different, pathways to fight disease. This new information should help researchers design more effective vaccines to prevent and fight diseases in horses. This fellowship training grant has also helped train a future veterinary scientist. (D07EQ-401)

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More Effective Drug Dosing for Allergic Skin Disease in Dogs

Friday, June 26th, 2009

dog

Study results:

Atopic dermatitis is a common allergic skin disease in dogs and humans. Antihistamines are commonly prescribed treatments, but there is a need to scientifically determine the optimal doses. With MAF funding, researchers validated the commonly used antihistamine, hydroxyzine, and determined that the optimal dose is twice daily rather than the current three times a day prescription. They also discovered that when hydroxyzine is administered orally or intravenously, the drug breaks down into its simpler form (cetirizine), and this simpler form is responsible for the actual antihistamine effect. Researchers now want to look at cetirizine for treating atopic dermatitis. (D07CA-029)

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Better Management Decisions for Elk and Cattle

Friday, June 26th, 2009

elk
Study results:

Scientists investigated brucellosis, a deadly infectious disease that causes abortion in elk and cattle and can also cause disease in people. This MAF study confirmed scientists’ theory that natural elk feeding grounds situated close to grazing cattle populations put elk at higher risk for abortions during calving season due to increased brucellosis infections. These results will allow state wildlife managers and ranchers to make informed decisions about managing the contact between elk and cattle populations. (D06ZO-084)

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Preventing Worm-Related Illnesses and Deaths in Camelids

Friday, June 26th, 2009

photo courtesy of Allan Dewald

Study results:

Gastrointestinal parasites are a leading cause of disease in llamas and alpacas. Resistance to de-wormer medications is thought to be prevalent, making worm-related illnesses, such as anemia, and deaths an increasing problem. With MAF funding, scientists studied hundreds of llamas and alpacas in the southeastern states and determined there is a very high prevalence of worm populations resistant to current medications. They also validated that the use of the FAMACHA eye color chart can be accurately used in llamas and alpacas to diagnose anemia. The need for further research into proper dosing of de-wormer medications specifically for llamas and alpacas is critical in preventing worm-related illnesses and deaths. (D06LA-011)

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Key Contributions to Horse Genome Map

Friday, June 26th, 2009

horse

Study results:

Treatment and prevention of many equine health issues suspected to have genetic risk factors rely on knowledge of how genes are organized and expressed. The gene-mapping research funded by MAF in this study was key to the successful assembly of the horse genome map. With the horse genome completely mapped, genetic research has catapulted into major discoveries of genetic mutations responsible for devastating diseases and disorders as well as genetic tests to diagnose, treat and prevent them. Scientists discovered the likely cause of night blindness in appaloosas, the genetic basis for the tobiano hair color pattern and the cause for polysaccharide storage myopathy, a form of “tying-up” in multiple breeds. (D05EQ-028)

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Simple, Noninvasive Method to Detect Heart Failure in Dogs

Friday, June 26th, 2009

photo courtesy of Wendy Dickie - Fine Eye Photography

Study results:

Congestive heart failure (CHF) is a common, often fatal condition in dogs suffering from heart diseases such as dilated cardiomyopathy and mitral valve disease. CHF causes fluid accumulation in the lungs with associated respiratory symptoms. Currently, chest X-rays or cardiac catheterization are used to diagnose CHF, but these methods expose veterinary personnel and canine patients to detrimental radiation and frequently require heavy sedation of the dog. Scientists successfully validated the use of a common, noninvasive ultrasound method, Doppler echocardiography, to diagnose CHF in dogs. This adapted use of ultrasound provides veterinarians with a simple and noninvasive tool for early detection and therapeutic monitoring of CHF. (D05CA-306)

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New Tool to Diagnose and Treat GI Disorders and Cancer in Cats

Friday, June 26th, 2009

photo courtesy of Patricia Olson

Study results:

Many cats suffer from gastrointestinal (GI) disorders, including inflammatory disorders and cancer. Proteins called trefoil peptides occur naturally in the GI tract and help to protect and repair it; however, abnormal levels of these proteins, whether high, low or even mutated, are associated with inflammation and cancer. With MAF funding, researchers successfully cloned these feline proteins, allowing them to measure the amount of these proteins in normal, inflamed and cancerous tissues. This new knowledge can now be used to better diagnose and treat cats with inflammatory bowel disease and cancer. (D04FE-026)

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More Realistic Diagnostic Ranges for Cat Nutrition and Health

Friday, June 26th, 2009

Photo courtesy of Suzanne Shaff Photography

Study results:

Veterinarians often use blood amino acid concentrations to assess feline nutritional health and diagnose certain medical conditions. Most of these concentrations were established in laboratory cats eating purified diets, which do not represent the household cat population. Funding from Morris Animal Foundation (MAF) enabled scientists to document and validate the largest and most complete blood amino acid concentrations published to date in household cats eating commercially available diets. This new information provides veterinarians with more appropriate ranges for pet cats, which in turn provides for better diagnosis of disease. (D08FE-048)

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